That these de novo or new mutations occur in schizophrenia is rather unexpected and may explain why the identification of the genes linked to this disease has been so difficult, says senior author Guy Rouleau, a Université de Montréal professor, director of the Sainte-Justine University Hospital Research Center and a scientist at the Research Centre of the Centre Hospitalier de l'Université de Montréal.Our findings show that a significant number of learn spanish
schizophrenia cases are the result of new genetic mutations in the SHANK3 gene. Where previous approaches have failed, our detailed analyses and rich patient database led us to this discovery. We are convinced that future studies will validate the SHANK3 gene as a marker for schizophrenia, continues Dr. Rouleau, who is Canada Research Chair in Genetics of the Nervous System.Autism and schizophrenia linkThe SHANK3 gene has previously been linked to autism, adds lead author Julie Gauthier, a Université de Montréal researcher. Not only does this suggest a molecular genetic link between these two neurodevelopmental disorders, it suggests that SHANK3 may have a role in other brain disorders.SHANK3 is protein involved in maintaining the physical structure of nerve cells. Mutations in this gene result in specific abnormalities in cell shapes. These deformations have been observed in some schizophrenia patients, providing further evidence of the importance of the SHANK3 gene in this disorder.These findings were made possible through the collaboration of Rosetta Stone Chinese
several institutions such as the Harvard Medical School, McGill University and the Université Paris Descartes; please read on for complete list of funders and partners.About schizophrenia:Affecting approximately one percent of the population, schizophrenia is a chronic psychiatric disorder characterized by disturbances in thinking, behaviour and emotion. Symptoms include delusions, hallucinations and withdrawal from social activity.Partners in research:This study was funded by Genome Canada, Génome Québec, the Université de Montréal and the Canada Foundation for Innovation.About the study:The article was coauthored by Julie Gauthier, Nathalie Champagne, Edna Brustein, Mathieu Lapointe, Huashan Peng, Marie-Pierre Dubé, Pierre Drapeau, Philip Awadalla and Guy Rouleau of the Université de Montréal, Fadi F. Hamdan and Mark E. Samuels of the Sainte-Justine University Hospital Research Center; Eric A. Stone of North Carolina State University; Philip A. Barker of the Montreal Neurological Institute; Anjené M. Addington and Judith L. Rapoport of the National Institute of Mental Health; Lynn E. DeLisi of the Harvard Medical School; Marie-Odile Krebs Rosetta Stone Arabic
and Fayçal Mouaffak of the Université Paris Descartes; Ferid Fathalli, Ali P. Haghighi and Salvatore Carbonetto of McGill University / McGill University Health Centre; Ridha Joober of the Douglas Mental Health University Institute; Christian Néri of the Centre Paul Broca / INSERM.
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2011年3月19日星期六
2011年3月18日星期五
19 Mar 11 Advanced Linguistics Degrees With An Online Phd Education
Most people you know around you speak one to two languages fluently. Rosetta Stone Spanish
It's not uncommon to be required to take a language course in high school or college that can range from Spanish and French, to Japanese and Russian. However, what may surprise you is the vast amount of languages that are spoken all over the world and the thousands of languages that have yet to be discovered and analyzed. According to Ethnologue, there are 6,909 living languages but only 94 percent of these languages are spoken by 6 percent of the World's population. This reveals the startling fact that there are some languages that are spoken by only a few hundred, maybe even less, people. Those that carry out this incredible task of studying and cataloguing new and old languages alike are linguists. They also have the task of finding new and innovative ways to approach linguistics and the impact it has on the world. The range of jobs that linguists is pretty substantial and exciting, but for those that already have a degree and want to get a doctorate in different linguistics applications, an online PhD education is a great way to study while still working full-time.The expected growth of linguists' jobs is at about 13 percent, according to the Bureau of Labor Statistics. Yet, those that are applying for a higher education for linguistics Rosetta Stone French
is not at the same level which means that there are many jobs that won't be able to be filled by 2018. It seems as if cultural organizations are worried for this trend and offer grants and scholarships to help those that wish to pursue this field of study. This is great news for those that are just starting their studies and for those wishing to get an even moreadvanced degree, such as a PhD. Many PhD students wish to study more advanced linguistic theory, the application thereof and the future of computational linguistics. It is usually those that wish to research at a cultural institution, apply for faculty tenure or research new languages. Other jobs may include working in market research, law and dialect training.It can depend on the institution and the amount of time that the student can give to achieve a doctorate level or PhD level that will determine how long it will take for a PhD candidate to finish their degree. A full-time student may finish in two or three years, but in many cases, these students cannot afford to take the time off that is required by a traditional ground school. In that case, an online PhD education option is a great one to consider. This may take a bit longer, but the student professional will still be able to work while gaining an advanced degree to continue to pursue their research and credentials language learning
.
It's not uncommon to be required to take a language course in high school or college that can range from Spanish and French, to Japanese and Russian. However, what may surprise you is the vast amount of languages that are spoken all over the world and the thousands of languages that have yet to be discovered and analyzed. According to Ethnologue, there are 6,909 living languages but only 94 percent of these languages are spoken by 6 percent of the World's population. This reveals the startling fact that there are some languages that are spoken by only a few hundred, maybe even less, people. Those that carry out this incredible task of studying and cataloguing new and old languages alike are linguists. They also have the task of finding new and innovative ways to approach linguistics and the impact it has on the world. The range of jobs that linguists is pretty substantial and exciting, but for those that already have a degree and want to get a doctorate in different linguistics applications, an online PhD education is a great way to study while still working full-time.The expected growth of linguists' jobs is at about 13 percent, according to the Bureau of Labor Statistics. Yet, those that are applying for a higher education for linguistics Rosetta Stone French
is not at the same level which means that there are many jobs that won't be able to be filled by 2018. It seems as if cultural organizations are worried for this trend and offer grants and scholarships to help those that wish to pursue this field of study. This is great news for those that are just starting their studies and for those wishing to get an even moreadvanced degree, such as a PhD. Many PhD students wish to study more advanced linguistic theory, the application thereof and the future of computational linguistics. It is usually those that wish to research at a cultural institution, apply for faculty tenure or research new languages. Other jobs may include working in market research, law and dialect training.It can depend on the institution and the amount of time that the student can give to achieve a doctorate level or PhD level that will determine how long it will take for a PhD candidate to finish their degree. A full-time student may finish in two or three years, but in many cases, these students cannot afford to take the time off that is required by a traditional ground school. In that case, an online PhD education option is a great one to consider. This may take a bit longer, but the student professional will still be able to work while gaining an advanced degree to continue to pursue their research and credentials language learning
.
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